Dynamic Polyconjugates™ Technology Platform


Dynamic polyconjugates are a delivery platform in development for siRNA.

"Dynamic Polyconjugates (DPCs) are small nanoparticles, 5-20 nanometers (nm) in size, composed of an amphipathic polymer to which shielding agents such as polyethylene glycol, as well as targeting ligands are reversibly attached. In some constructs, the siRNA payload is attached to the DPC, while in other constructs, the siRNA circulates attached to a different carrier. When attached, the DPC construct protects the siRNA payload while allowing the polymer to circulate in the blood without creating undue toxicity."


Information Verified: 
April, 2013

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