Spectrum Laboratories

Company Background

Spectrum Laboratories, founded in 1970, specializes in bio-separation and cell line management (1a). They are considered a pioneer in dialysis membranes and accessories, disposable hollow fiber filtration modules and systems, supported polymeric liquid membranes and preparative low-pressure chromatography products (1a). They have significant involvement in R&D and offer over 2,000 products ranging from small disposable membranes to high-volume systems (1a). Spectrum Laboratories has headquarters in Rancho Dominguez, California; Houston, Texas; and Dallas, Texas, with sales offices in Breda, Netherlands and Otsu-city, Shiga, Japan (1a). Roy Eddleman is the founder of Spectrum Labs (1b).

Suppliers and Buyers

Spectrum Laboratories has distributors from around the world that are responsible for representing their myriad of product lines (1d). The company’s OEM Group partners with organizations to aid them in R&D, design, packaging and regulatory support (1c).

Innovation and Technology

Spectrum is engaged in developing and manufacturing ultrafiltration membranes for process filtration applications. Spectrum offers low protein binding polysulfone hollow fiber membranes with 10 kD, 50 kD, 400 kD, 500 kD (20 nm) and 1,000 kD (0.05 µm) and surface areas ranging from 8 square cm to 5.1 square meters (1h).

The single-use Modified Polyethersulfone (mPES) hollow hiber hilters developed by Spectrum Labs are used for tangential flow filtration (TFF) (1e). The use of polyethersulfone provides “higher flux rates for faster processing, excellent selectivity for separation applications and low protein biding for higher yields” (1e).  These filters reduce cost for users, creating a faster processing time, decreasing the cost of labor and reducing the use of WFI (1e).

When used in conjunction with the mPES filters, Spectrum Lab’s KrosFlo Research lli Tangential Flow Filtration System provides “faster and gentler washing, purification, and concentration of cells, proteins, viruses and nanoparticles” (1f). This system works particularly well in R&D scale microfiltration and ultrafiltration processing (1f).

In 2010, Spectrum Laboratories sent two of their products into space with the Space Shuttle Discovery (1g). The Cell Max Bioreactors were used to study stem cell differentiation in space and to provide new information concerning wound healing and tissue regeneration (1g). The Stock Bioreactor was used to study the effect of bacterial infection on mammalian epithelial cells in space. The results of these studies were meant to determine the differentiation of infections in human cells in space as opposed to on Earth (1g).

Sources

  1. Spectrum Laboratories (2012). Retrieved on December 4, 2012 from www.spectrumlabs.com
    1. www.spectrumlabs.com/generic/profile.html
    2. www.spectrumlabs.com/generic/art.html
    3. www.spectrumlabs.com/oem
    4. www.spectrumlabs.com/i18n/distributors.html
    5. www.spectrumlabs.com/generic/press/press7.pdf
    6. www.spectrumlabs.com/generic/press/press6.pdf
    7. www.spectrumlabs.com/generic/press/press5.pdf
    8. www.spectrumlabs.com/filtration/FundFilt.html